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Veterinary Pathology, Vol 33, Issue 4 434-436, Copyright © 1996 by American College of Veterinary Pathologists
ARTICLES |
M. Pumarola, S. Anor, D. Borras and I. Ferrer
Department of Pathology and Animal Production, School of Veterinary Medicine, Campus UAB, Bellaterra, Barcelona, Spain.
A malignant epithelioid schwannoma was diagnosed affecting the trigeminal nerve of an 11-year-old dog. Neurologic abnormalities included an altered mental status, ataxia, left head tilt, postural reaction deficits of all four limbs, a pronounced left masticatory muscle atrophy, and absent left facial sensation. Histologically, a densely arranged epithelioid population with a very high mitotic index was surrounded by a spindle-shaped cell proliferation characteristic of schwannomas. Both cell populations stained positively for vimentin, but only spindle cells were occassionally positive for S-100 protein. The histologic and immunohistochemical features of this tumor were consistent with those found in human epithelioid schwannomas.
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