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Veterinary Pathology, Vol 34, Issue 1 52-54, Copyright © 1997 by American College of Veterinary Pathologists

ARTICLES

Immunohistochemical demonstration of equine herpesvirus-1 antigen in neurons and astrocytes of horses with acute paralysis

P. C. Schultheiss, J. K. Collins and S. F. Hotaling
Veterinary Diagnostic Laboratory, Colorado State University, Fort Collins 80526, USA.

Equine herpesvirus-1 (EHV-1) infection in a few widely scattered neurons and astrocytes plus endothelial cells in brain and spinal cord of two horses with naturally occurring paralytic disease was demonstrated by use of an immunoperoxidase technique. These horses were euthanatized less than 48 hours after the onset of clinical signs. No staining for EHV-1 was demonstrated in brain or spinal cord of three horses that had a longer duration of clinical disease or in two uninfected horses.


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[Abstract] [Full Text] [PDF]


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