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Veterinary Pathology, Vol 35, Issue 5 409-411, Copyright © 1998 by American College of Veterinary Pathologists
ARTICLES |
Y. Noda, Y. Uchinuno, H. Shirakawa, S. Nagasue, N. Nagano, R. Ohe and M. Narita
Ryochiku Livestock Hygiene Service Center, Kurume, Fukuoka, Japan.
A bovine fetus aborted at 187 days of gestation was serologically and immunohistopathologically examined. Serum and cerebrospinal fluid samples had high titers of virus-neutralizing antibody for Aino virus. A severe necrotizing encephalopathy was noted. Aino virus antigen was demonstrated in neuroglial cells within the brain lesion. The destruction of developing neuronal cells appeared to be a significant feature of the pathogenesis of lesions due to Aino virus infection in the central nervous system.
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