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Mammary Adenocarcinoma in a Male Squirrel Monkey (Saimiri sciureus)

Abstract

A nodule was identified within the right mammary gland of a 16-year-old male squirrel monkey (Saimiri sciureus). The mass was excised and diagnosed as a mammary adenocarcinoma. The monkey developed congestive heart failure 1.5 years later and was euthanatized. At necropsy, a subcutaneous mass was found in the right axillary region. Histologically, the mass was identified as a lymph node whose architecture was effaced by neoplastic cells resembling those of the mammary tumor. Metastasis to internal organs was not observed. This is the first reported case of a mammary tumor in a New World primate and the only known case of mammary cancer in a male nonhuman primate.

Key words: Mammary neoplasms; primates; Saimiri.

Request reprints from Dr. R. J. Tolwani, Department of Comparative Medicine, School of Medicine, Stanford University, Stanford, CA 94305-5410 (USA).