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Vet Pathol 37:692-695 (2000)
© 2000 American College of Veterinary Pathologists
BRIEF COMMUNICATIONS AND CASE REPORTS

Transitional Cell Carcinoma of the Urinary Bladder in a Thoroughbred, with Intra-abdominal Dissemination

J. C. Patterson-Kane, R. R. Tramontin, R. C. Giles, Jr. and L. R. Harrison

Abstract

A 14-year-old Thoroughbred gelding with a history of acute onset of hematuria was presented for necropsy. Transitional cell carcinoma of the urinary bladder with intra-abdominal dissemination was diagnosed. Tumor masses were observed on the splenic capsule and surrounding the distal abdominal aorta. Tumor cells showed diffuse cytoplasmic reactivity for cytokeratin but were negative for epithelial membrane antigen, carcinoembryonic antigen, tumor-associated glycoprotein 72, and vimentin.

Key words: Horses; immunohistochemistry; transitional cell carcinoma; urinary bladder.

Request reprints from Dr. L. Harrison, Livestock Disease Diagnostic Center, 1429 Newtown Pike, Lexington, KY 40511 (USA).






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