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Vet Pathol 39:679-689 (2002)
© 2002 American College of Veterinary Pathologists


ANIMAL MODELS

Traumatic Brain Injury

J. W. Finnie and P. C. Blumbergs

Veterinary Services Division, Institute of Medical & Veterinary Science (JWF), Division of Tissue Pathology, Institute of Medical & Veterinary Science (PCB), and Department of Pathology, University of Adelaide, Australia (JWF, PCB)

Animal models have played a critical role in elucidating the complex pathogenesis of traumatic brain injury, the major cause of death and disability in young adults in Western countries. This review discusses how different types of animal models are useful for the study of neuropathologic processes in traumatic, blunt, nonmissile head injury.


Key words: Animal models; neuropathology; pathogenesis; traumatic brain injury.

Request reprints from Prof. P. C. Blumbergs, Neuropathology, Institute of Medical & Veterinary Science, Frome Road, Adelaide 5000 (Australia). E-mail: peter.blumbergs{at}imvs.sa.gov.au.




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