This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via ISI Web of Science (1) Citing Articles via Google Scholar Google Scholar Articles by Esplin, D. G. Articles by Hullinger, G. A. Search for Related Content PubMed PubMed Citation Articles by Esplin, D. G. Articles by Hullinger, G. A.

Squamous Cell Carcinoma of the Anal Sac in Five Dogs

Abstract

Tumors of the perianal area of dogs are common and include multiple tumor types. Whereas perianal adenomas occur often, adenocarcinomas of the apocrine glands of the anal sac occur less frequently. A review of the literature revealed no reports of squamous cell carcinomas arising from the epithelial lining of the anal sac. Squamous cell carcinomas originating from the lining of the anal sac were diagnosed in five dogs. Microscopically, the tumors consisted of variably sized invasive nests and cords of epithelial cells displaying squamous differentiation. Four of the five dogs were euthanatized because of problems associated with local infiltration by the tumors. In the fifth dog, there was no evidence of tumor 7 months after surgical removal, but further follow up was not available.

Key words: Anal sac; canine; squamous cell carcinoma.

Request reprints from Dr. D. Glen Esplin, Animal Reference Pathology Division, ARUP Laboratories, 500 Chipeta Way, Salt Lake City, UT 84108 (USA). E-mail: esplindg{at}aruplab.com.