This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (10) Citing Articles via Google Scholar Google Scholar Articles by Stoica, G. Articles by Coates, J. R. Search for Related Content PubMed PubMed Citation Articles by Stoica, G. Articles by Coates, J. R. Social Bookmarking                            What's this?

Morphology, Immunohistochemistry, and Genetic Alterations in Dog Astrocytomas

Departments of Veterinary Pathobiology (GS, H-TK) and Small Animal Medicine and Surgery (JRC), College of Veterinary Medicine, Texas A&M University, College Station, TX; and Texas Veterinary Medical Diagnosis Laboratory (GDH), College Station, TX

Astrocytoma is one of the most common tumors of the central nervous system in animals. Of the domesticated animal species, most examples are seen in dogs, and the spectrum that has been described is quiet broad. Previous studies have revealed morphologic similarities between human and animal astrocytomas. Human astrocytomas are often associated with genetic alterations that determine the clinical behavior and therapy outcome. The purpose of this study was to further characterize astrocytomas in dogs and to determine whether there are genetic changes similar to those in the human counterpart.

Key words: Dog astrocytoma; genetic alterations; morphology.

Request reprints from Dr. G. Stoica, Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843-4467 (USA). E-mail: gstoica{at}cvm.tamu.edu.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Facebook    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				G. Stoica, G. Lungu, H. Martini-Stoica, S. Waghela, J. Levine, and R. Smith Identification of Cancer Stem Cells in Dog Glioblastoma Vet. Pathol., May 1, 2009; 46(3): 391 - 406. [Abstract] [Full Text] [PDF]

				F. Aloisio, J. M. Levine, and J. F. Edwards Immunohistochemical features of a feline spinal cord gemistocytic astrocytoma J Vet Diagn Invest, November 1, 2008; 20(6): 836 - 838. [Abstract] [Full Text] [PDF]

				C. J. Gibson, N. M. A. Parry, R. M. Jakowski, and D. Eshar Anaplastic Astrocytoma in the Spinal Cord of an African Pygmy Hedgehog (Atelerix albiventris) Vet. Pathol., November 1, 2008; 45(6): 934 - 938. [Abstract] [Full Text] [PDF]

				J. Kimmelman and J. Nalbantoglu Faithful Companions: A Proposal for Neurooncology Trials in Pet Dogs Cancer Res., May 15, 2007; 67(10): 4541 - 4544. [Abstract] [Full Text] [PDF]

				S. A. M. Thomson, E. Kennerly, N. Olby, J. R. Mickelson, D. E. Hoffmann, P. J. Dickinson, G. Gibson, and M. Breen Microarray Analysis of Differentially Expressed Genes of Primary Tumors in the Canine Central Nervous System Vet. Pathol., September 1, 2005; 42(5): 550 - 558. [Abstract] [Full Text] [PDF]

				J. R. Cowart, F. Y. Schulman, and H. Mena Low-grade Glial Tumor with Features of Astroblastoma in a Dog Vet. Pathol., May 1, 2005; 42(3): 366 - 369. [Abstract] [Full Text] [PDF]