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Vet Pathol 42:374-377 (2005)
© 2005 American College of Veterinary Pathologists
BRIEF COMMUNICATIONS AND CASE REPORTS

Combined-type Osteosarcoma in a Rhesus Macaque

S. L. Beam

Abstract

A femoral mass from a 15-year-old rhesus macaque was evaluated. Grossly, the mass consisted of a large, osteolytic focus in the distal femur, a gelatinous core of neoplastic tissue in the medullary cavity, and an invasive mass-obliterating musculature of the thigh. On histopathologic evaluation, three neoplastic mesenchymal cell populations, osteoblasts, fibroblasts, and primitive mesenchymal cells were identified. The mass was diagnosed as a combined type osteosarcoma. To our knowledge, this is the first osteosarcoma in a rhesus macaque with this subclassification.

Key words: Bone neoplasia; combined type osteosarcoma; Macaca mulatta; rhesus macaques.




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