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Vet Pathol 43:198-201 (2006)
© 2006 American College of Veterinary Pathologists
BRIEF COMMUNICATIONS AND CASE REPORTS

Deciduoid Peritoneal Mesothelioma in a Dog

M. Morini, G. Bettini, F. Morandi, R. Burdisso and P. S. Marcato

Abstract

Deciduoid mesothelioma is a rare variant of epithelial mesothelioma, up to now only described in human pathology, which bears remarkable cytomorphologic resemblance to the endometrium of pregnancy, termed decidua. A case of peritoneal mesothelioma with deciduoid features in a 10-year-old, female dog is reported. Multiple whitish-gray nodules (1–5 mm in diameter) in parietal peritoneum and mesentery were histologically composed of large, proliferating, polygonal or ovoid cells with an abundant eosinophilic, glassy cytoplasm. Immunohistochemical evaluation indicated that the neoplastic cells coexpressed cytokeratin and vimentin with strong and diffuse cytoplasmic staining, and ultrastructural analysis showed long and slender mesothelial-type microvilli; these findings confirmed the mesothelial origin of the tumor.

Key words: Deciduoid mesothelioma; dog; mesothelioma; peritoneum.

Request reprints from Dr. M. Morini, Dipartimento di Sanità Pubblica Veterinaria e Patologia Animale, Servizio di Anatomia Patologica, Università degli Studi di Bologna, via Tolara di Sopra 50, 40064 Ozzano Emilia, Bologna (Italy). E-mail: bettini{at}vet.unibo.it.




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[Abstract] [Full Text] [PDF]


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