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Vet Pathol 44:247-249 (2007)
© 2007 American College of Veterinary Pathologists
BRIEF COMMUNICATIONS AND CASE REPORTS

Equine Osteosarcoma: A Series of 8 Cases

J. M. Bush, R. L. Fredrickson and E. J. Ehrhart

Colorado State University, Department of Microbiology, Immunology, and Pathology, Fort Collins, CO (JMB, EJE); and University of Illinois, Department of Pathobiology, Urbana-Champaign, IL (RLF)

Abstract

In horses, osteosarcoma is a rare tumor, with the majority of reported cases occurring in the head, and, more specifically, in the mandible of young horses. The following report documents 8 cases of equine osteosarcoma, the majority occurring in male horses aged 7 years or older with a lack of metastasis identified in any horse. Six arose in the maxilla or mandible and one in the proximal tibia. The predominant subtype was fibroblastic osteosarcoma with fewer osteoblastic type tumors. All had osteoid and most had a chondromucinous matrix. Surgical excision was attempted in the majority of cases. An inability to completely excise the tumor and progressive disease typically resulted in euthanasia. To the authors' knowledge, this case series also documents the first report of an equine extraosseous osteosarcoma within the subcutaneous tissue caudal to the shoulder. Surgical excision appears successful with no recurrence of disease 14 months later. Further investigations of equine osteosarcoma and various chemotherapeutic agents are warranted to present additional treatment options.

Key words: Equine; facial; mandible; maxilla; neoplasia; osteosarcoma.

Request reprints from Jamie Bush, Colorado State University, Department of Microbiology, Immunology, and Pathology, 1619 Campus Delivery, Fort Collins, CO 80523-1619 (USA). E-mail: Jamie.Bush{at}ColoState.edu






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Copyright © 2007 by the American College of Veterinary Pathologists.