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Vet Pathol 44:504-507 (2007)
© 2007 American College of Veterinary Pathologists
BRIEF COMMUNICATIONS AND CASE REPORTS

Orbital (Retrobulbar) Meningioma in a Simmental Cow

J. L. Reis, C. T. Kanamura, G. M. Machado, R. O. França, J. R. J. Borges and R. L. Santos

Faculdade de Agronomia e Medicina Veterinária, Universidade de Brasília, Brasília, DF, Brazil (JLRJr, GMM, ROF, JRJB), Divissõ de Patologia, Instituto Adolfo Lutz, São Paulo, SP, Brazil (CTK). Departamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária da Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil (RLS)

Abstract

A 12-year-old Simmental cow was presented with a moderately firm irregular whitish mass of approximately 5 cm in diameter, occupying the right orbit. Microscopically, a poorly differentiated neoplasm was observed. The immunohistochemical panel included cytokeratins, vimentin, epithelial membrane antigen, Factor VIII, CD34, Mart-1, Melan A, smooth muscle actin, desmin, chromogranin, neuron-specific enolase, S-100 protein, and MIB-1. The neoplasm was negative for all of them, with the exception of vimentin and S-100 protein. Transmission electron microscopy revealed abundant desmosomes. These findings support the diagnosis of orbital (retrobulbar) meningioma.

Key words: Bovine; cattle; orbital meningioma.

Request reprints from Dr. R. L. Santos, Escola de Veterinária da UFMG, Depto. Clínica e Cirurgia Veterinárias, Av. Antônio Carlos, 6627, 31270-901, Belo Horizonte, MG (Brazil). E-mail: rsantos{at}vet.ufmg.br






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