This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Ochi, A. Articles by Umemura, T. PubMed PubMed Citation Articles by Ochi, A. Articles by Umemura, T.

Naturally Occurring Multiple Perineuriomas in a Chicken (Gallus domesticus)

Laboratory of Comparative Pathology, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan

Abstract

A 2-year-old, male Japanese native fowl (Gallus gallus domesticus) was presented with an inability to feed and torticollis. At a necropsy, there were cylindrical enlargements and yellow discoloration of multiple peripheral nerves, including nerves of the lumbosacral plexus, brachial plexus, and spinal ganglia. On histologic examination, these lesions consisted of diffuse proliferations of spindle cells with characteristic onion bulb–like structures around residual axons. The spindle cells were immunohistochemically positive for glucose transporter 1 (GLUT1) and negative for S-100 /β proteins. On the basis of microscopic, histologic, and immunohistochemical findings, the tumors were diagnosed as multiple perineuriomas.

Key words: Avian leukosis virus (ALV); chicken; fowl glioma; immunohistochemistry; polymerase chain reaction (PCR); perineurioma; peripheral nerve.

Request reprints from Kenji Ochiai, Laboratory of Comparative Pathology, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, (Japan). E-mail: k-ochiai{at}vetmed.hokudai.ac.jp