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Vet Pathol 45:949-951 (2008)
© 2008 American College of Veterinary Pathologists


COLUMNS

Diagnostic Exercise: Astrocytoma with Involvement of Medulla Oblongata, Spinal Cord, and Spinal Nerves in a Raccoon (Procyon lotor)

A. N. Hamir, R. Picton, L. L. Blythe and J. R. Heidel

College of Veterinary Medicine, Oregon State University, Magruder Hall, Corvallis, OR1

Abstract

Neoplasms affecting the central and peripheral nervous systems of wild animals are extremely rare. Described are clinical signs and pathologic and immunohistochemical findings in an adult female raccoon (Procyon lotor) with an astrocytoma that involved medulla, cervical spinal cord, and roots of the cervical spinal nerves. Microscopically, the neoplastic cells revealed some pleomorphism but generally had fusiform morphology and showed moderate numbers of mitotic figures. Glial fibrillary acidic protein was demonstrated within the neoplastic cells by immunohistochemistry. This appears to be the only reported case of astrocytoma that involved multiple anatomic sites in the central nervous system of this raccoon.


Key words: Astrocytoma (brain, spinal cord, nerves); glial fibrillary acidic protein (GFAP); raccoons (Procyon lotor).

Request reprints from Dr. Amir N Hamir, National Animal Disease Center, ARS, USDA, 2300 Dayton AvenuePO Box 70,, Ames, IA 50010 (USA). E-mail: Amir.Hamir{at}ars.usda.gov







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